产品详情
产品名称HMGCS2 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human HMGCS2 (NP_005509.1).
标记Unconjugated
别名HMGCS2
数据库入口号GeneID:3158
Swiss Prot:P54868
Uniprot
P54868
计算分子量50kDa/52kDa/56kDa
实际分子量50kDa
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 81% glycerol.
保存Store at -20˚C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.34.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using HMGCS2 antibody at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human thyroid cancer using HMGCS2 antibody at dilution of 1:100 .
Immunohistochemistry of paraffin-embedded human colon carcinoma using HMGCS2 antibody at dilution of 1:100 .
Immunofluorescence analysis of rat liver using HMGCS2 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.
Immunofluorescence analysis of human liver using HMGCS2 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.
Immunofluorescence analysis of mouse liver using HMGCS2 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.
The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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et al,Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissueInClin ProteomicsOn2023 Dec 1bySufei Song?1,?Jixian Zheng?2 et al..PMID:?38036981
, (2023),
PMID:
38036981
Yes
