产品详情
产品名称DCN Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human DCN (NP_598010.1).
标记Unconjugated
别名DCN;CSCD;DSPG2;PG40;PGII;PGS2;SLRR1B;decorin;Decorin
数据库入口号Uniprot:P07585
GeneID:1634
Uniprot
P07585
Gene ID
1634
计算分子量8kDa/19kDa/23kDa/27kDa/39kDa
实际分子量45KDa/48KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using DCN antibody.
Western blot analysis of extracts of HeLa cells, using DCN antibody.
Immunofluorescence analysis of NIH-3T3 cells using DCN Rabbit pAb.
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.
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et al,Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1InExp Mol MedOn2023 JulbyShanxi Wang 1, Yunkun Qu 1, et al..PMID: 37394592
, (2023),
PMID:
37394592
Yes
