产品详情
产品名称TREM2 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human TREM2 (NP_061838.1).
标记Unconjugated
别名TREM2;TREM-2;Trem2a;Trem2b;Trem2c
数据库入口号GeneID:54209
Swiss Prot:Q9NZC2
Uniprot
Q9NZC2
计算分子量24kDa/25kDa
实际分子量25kDa
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 104% glycerol.
保存Store at -20˚C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.57.
应用详情
WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:20 - 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer using TREM2 antibody at dilution of 1:200 .
Immunohistochemistry of paraffin-embedded mouse spleen using TREM2 antibody at dilution of 1:200 .
Immunofluorescence analysis of mouse lung cells using TREM2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-251MG cells using TREM2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of Mouse brain, using TREM2 antibody at 1:1000 dilution.
Immunofluorescence analysis of Rat lung using TREM2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded human tonsil using TREM2 antibody at dilution of 1:200 .
Immunohistochemistry of paraffin-embedded human colon carcinoma using TREM2 antibody at dilution of 1:200 .
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
如果您使用该产品29208发表了文章，请通知我们，让我们可以引用您的文献。
et al,Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease. In Inflamm Regen
on 2022 Aug 3 by Xiao-Gang Zhou, Wen-Qiao Qiu,et al..PMID:35918778
, (2022),
PMID:
35918778
Yes
