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Claudin-1 Antibody#29226

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产品详情

产品名称Claudin-1 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Affinity-chromatography

应用WB IHC

种属反应性Human;Mouse;Rat

特异性Claudin 1 antibody detects endogenous levels of total Claudin 1

免疫原类型Peptide

免疫原描述A synthesized peptide derived from human Claudin 1

基因/蛋白名称Claudin-1

标记Unconjugated

别名claudin 1; Claudin-1; CLD1; CLDN1; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1

数据库入口号Swiss-Prot#: O95832

Uniprot O95832

实际分子量22KD

浓度1.0mg/ml

配方Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

保存Store at -20°C/1 year

应用详情
WB: 1:500~1:3000
IHC: 1:50~1:200
Western blot analysis on HeLa cell lysate using Claudin 1 Antibody

 Claudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins.

如果您使用该产品29226发表了文章,请通知我们,让我们可以引用您的文献。

et al,Fecal microbiota transplantation mitigates bone loss by improving gut microbiome composition and gut barrier function in aged rats. In PeerJ on 2021 Oct 21 by Sicong Ma, Ning Wang, et al..PMID:34721980 , (2021),
PMID: 34721980
et al,Gut Microbiota Dysbiosis as One Cause of Osteoporosis by Impairing Intestinal Barrier Function. In Calcif Tissue Int on 2022 Feb by Ning Wang, Sicong Ma, et al..PMID:34480200 , (2022),
PMID: 34480200

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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