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PINK1 Rabbit Polyclonal Antibody#29297

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产品详情

产品名称PINK1 Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IF

种属反应性Human;Mouse;Rat

免疫原描述Recombinant fusion protein of human PINK1 (NP_115785.1).

标记Unconjugated

别名PINK1;BRPK;PARK6

数据库入口号Swiss Prot:Q9BXM7
GeneID:65018

Uniprot Q9BXM7

计算分子量30kDa/62kDa

实际分子量50kDa

配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1:500 - 1:2000
IF 1:50 - 1:200
 

Immunofluorescence analysis of HeLa cells using PINK1 . Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PINK1 at 1:1000 dilution.

This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.

如果您使用该产品29297发表了文章，请通知我们，让我们可以引用您的文献。

et al,Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease. In Exp Cell Res on 2020 Nov 1 by Xiaomin Xiong, Shijie Li, et al..PMID: 32905804 , (2020),
PMID: 32905804
et al,Dietary High-Fat Promotes Cognitive Impairment by Suppressing MitophagyInOxid Med Cell LongevOn2023 Jan 21byOxid Med Cell Longev et al..PMID:?36718278 , (2023),
PMID: 36718278
et al,Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission. In Mol Cell Biochem on 2024 Jul 13 by Haixia Fan, Minghao Yuan,et al..PMID:38997506 , (2024),
PMID: 38997506
et al,Xinyin tablets affect mitophagy and cardiomyocyte apoptosis to alleviate chronic heart failure by regulating histone deacetylase 3(HDAC3)-mediated PTEN induced putative kinase 1(PINK1)/Parkin signaling pathway. , (2025),
PMID: 40122315

操作手册

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡
;

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