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位置: 首页 > 多克隆抗体 > LGR5 Rabbit Polyclonal Antibody

LGR5 Rabbit Polyclonal Antibody#29562

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产品详情

产品名称LGR5 Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB;IHC

种属反应性Mouse;Rat

免疫原描述Recombinant fusion protein of human LGR5 (NP_003658.1).

标记Unconjugated

别名LGR5;FEX;GPR49;GPR67;GRP49;HG38

数据库入口号Swiss Prot:O75473
GeneID:8549

Uniprot O75473

计算分子量100kDa(其中SDS-PAGE MW删除)保留一种分子量就行

实际分子量105kDa

浓度2.92 mg/mL

配方PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情
WB 1:1000 - 1:5000
IHC-P 1:100 - 1:500
Western blot analysis of lysates from Mouse brain using LGR5/GPR49 Rabbit pAb at 1:2000 dilution.
Immunohistochemistry analysis of paraffin-embedded Rat brain using LGR5/GPR49 Rabbit pAb at dilution of 1:300 (40x lens).
Immunohistochemistry analysis of paraffin-embedded Rat lung using LGR5/GPR49 Rabbit pAb at dilution of 1:300 (40x lens).
Immunohistochemistry analysis of paraffin-embedded Rat ovary using LGR5/GPR49 Rabbit pAb at dilution of 1:300 (40x lens).

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

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et al,Dietary emulsifier Polysorbate 80-induced lipotoxicity promotes intestinal senescence , (2025),
PMID:

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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