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位置: 首页 > 多克隆抗体 > BDNF Rabbit Polyclonal Antibody

BDNF Rabbit Polyclonal Antibody#29683

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产品详情

产品名称BDNF Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB,IF

种属反应性Human;Mouse

免疫原描述Recombinant fusion protein of human BDNF (NP_733928.1).

标记Unconjugated

别名BDNF;ANON2;BULN2

数据库入口号Swiss Prot:P23560
GeneID:627

Uniprot P23560

计算分子量27kDa/28kDa/29kDa/31kDa/37kDa

实际分子量15kDa/35kDa

配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1:500 - 1:2000
IF 1:50 - 1:200

Immunofluorescence analysis of U-251MG cells using BDNF at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of U-251MG cells, using BDNF at 1:1000 dilution.
Western blot analysis of extracts of various cell lines, using BDNF at 1:1000 dilution.

This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

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et al,Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization. , (2025),
PMID: 39891150

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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