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位置: 首页 > 多克隆抗体 > BGLAP Rabbit Polyclonal Antibody

BGLAP Rabbit Polyclonal Antibody#29697

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产品详情

产品名称BGLAP Rabbit Polyclonal Antibody

来源种属Rabbit

克隆性Polyclonal

亚型IgG

纯化Affinity purification

应用WB IF

种属反应性Human;Mouse;Rat

免疫原描述A synthetic peptide of human BGLAP (NP_954642.1).

标记Unconjugated

别名BGLAP;BGP;OC;OCN;osteocalcin

数据库入口号Swiss Prot:P02818
GeneID:632

Uniprot P02818

计算分子量11kDa

实际分子量11kDa

配方Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保存Store at -20˚C. Avoid freeze / thaw cycles.

应用详情

WB 1:500 - 1:2000

Western blot analysis of extracts of mouse pancreas, using BGLAP at 1:1000 dilution.
Immunofluorescence analysis of MG-63 cells using BGLAP Rabbit pAb at dilution of 1:200. Blue: DAPI for nuclear staining.

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

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et al,An electrostatic encapsulation strategy to motivate 3D-printed polyelectrolyte scaffolds for repair of osteoporotic bone defects. , (2025),
PMID: 39719966

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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