产品详情
产品名称CYSLTR1 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse
免疫原描述A synthetic peptide of human CYSLTR1 (NP_006630.1).
标记Unconjugated
别名CYSLTR1; CYSLT1; CYSLT1R; CYSLTR; HMTMF81; cysteinyl leukotriene receptor 1
数据库入口号Swiss-Prot#:Q9Y271
NCBI Gene ID:10800
Uniprot
Q9Y271
计算分子量38kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using CYSLTR1 antibody at 1:1000 dilution.
This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
如果您使用该产品30332发表了文章，请通知我们，让我们可以引用您的文献。
et al,Oxytropis falcata bunge extract combined with black soybean oil ameliorates DNCB-induced atopic dermatitis-like skin inflammation
, (2025),
PMID:
40612737
Yes
