产品详情
产品名称PPAR alpha Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Mouse
免疫原描述A synthetic peptide of human PPAR alpha
标记Unconjugated
别名PPARA; NR1C1; PPAR; PPARalpha; hPPAR; peroxisome proliferator-activated receptor alpha
数据库入口号Swiss-Prot#:Q07869
NCBI Gene ID:5465
Uniprot
Q07869
计算分子量52kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:1000
Western blot analysis of extracts of Mouse kidney, using PPAR alpha antibody.
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
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et al,Dietary emulsifier Polysorbate 80-induced lipotoxicity promotes intestinal senescence
, (2025),
PMID:
Yes
