产品详情
产品名称TNFAIP6 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human TNFAIP6 (NP_009046.2).
标记Unconjugated
别名TNFAIP6;TSG-6;TSG6
数据库入口号Uniprot:P98066
GeneID:7130
Uniprot
P98066
Gene ID
7130
计算分子量40kDa
实际分子量40kDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of mouse brain, using TNFAIP6 Antibody.
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
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et al,A pyroptosis-related gene signature that predicts immune infiltration and prognosis in colon cancerInFront OncolOn2023 Jul 12byMingjian Wu?1,?Shuai Hao et al..PMID:?37503314
, (2023),
PMID:
37503314
Yes
