产品详情
产品名称NLRC4 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human NLRC4 (NP_067032.3).
标记Unconjugated
别名NLRC4;AIFEC;CARD12;CLAN;CLAN1;CLANA;CLANB;CLANC;CLAND;CLR2.1;FCAS4;IPAF
数据库入口号Uniprot:Q9NPP4
GeneID:58484
Uniprot
Q9NPP4
Gene ID
58484
计算分子量116kDa
实际分子量110KDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of Mouse large intestine, using NLRC4 antibody.
Immunofluorescence analysis of NIH-3T3 cells using NLRC4 Rabbit pAb.
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
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et al,Increased reactive astrocytes and NLRC4-mediated neuronal pyroptosis in advanced visual structures contralateral to the optic nerve crush eye in mice.
, (2025),
PMID:
39798846
Yes
