产品详情
产品名称LDHB Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
免疫原描述Recombinant fusion protein of human LDHB (NP_002291.1).
标记Unconjugated
别名LDHB;HEL-S-281;LDH-B;LDH-H;LDHBD;TRG-5
数据库入口号Uniprot:P07195
GeneID:3945
Uniprot
P07195
Gene ID
3945
计算分子量37kDa
实际分子量37kDa
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using LDHB antibody.
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
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et al,Identification of lactate metabolism-related genes for glioma metabolic reprogramming
, (2022),
PMID:
Yes
