产品详情
产品名称YWHAZ Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
免疫原描述A synthetic peptide of human YWHAZ (NP_001129171.1).
标记Unconjugated
别名YWHAZ; 14-3-3-zeta; HEL-S-3; HEL-S-93; HEL4; KCIP-1; YWHAD; 14-3-3 protein zeta/delta
数据库入口号Swiss-Prot#:P63104
NCBI Gene ID:7534
Uniprot
P63104
计算分子量28kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded rat brain using YWHAZ antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using YWHAZ antibody at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using YWHAZ antibody at 1:1000 dilution.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
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et al,Neurohypophysial and paracrine vasopressinergic signaling regulates aquaporin trafficking to hydrate marine teleost oocytes
, (2023),
PMID:
37635977
Yes
