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FGF7 Antibody#31162

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产品详情

产品名称FGF7 Antibody

来源种属Rabbit

克隆性Polyclonal

应用ELISA WB IHC

种属反应性Human;Mouse;Rat

特异性The antibody detects endogenous level of total FGF7 protein.

免疫原类型Peptide

免疫原描述Synthetic peptide corresponding to a region derived from 179-182 amino acids of Human Fibroblast growth factor 7

基因/蛋白名称FGF7

标记Unconjugated

别名Fibroblast growth factor 7 , KGF, HBGF-7

数据库入口号Swiss-Prot:P21781
Gene ID:860

Uniprot P21781

浓度0.4mg/ml

配方Supplied at 2.5mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

保存Store at -20˚C/1 year

应用详情

Predicted MW: 23kd
ELISA: 1:500-1:5000
Western blotting: 1:1000-1:3000
Immunohistochemistry: 1:50-1:200

Gel: 10%SDS-PAGE
Lane1: Human gastric cancer tissue lysate
Lane2: Human esophagus cancer tissue lysate
Lysate: 40ug
Primary antibody: 1/1250 dilution
Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/5000 dilution
Exposure time: 1 second
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 31162 (FGF7 Antibody) at dilution 1/15, on the right is treated with the synthetic peptide.

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

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et al,Maldevelopment of the submandibular gland in a mouse model of apert syndrome.In Dev Dyn. On 2018 Nov by Yamaji K, Morita J et al..PMID:30251381 , (2018),
PMID: 30251381
et al,Maldevelopment of the submandibular gland in a mouse model of apert syndrome.In Dev Dyn. On 2018 Nov by Yamaji K, Morita J et al..PMID:30251381 , (2018),
PMID: 30251381
et al,Ser252Trp mutation in fibroblast growth factor receptor 2 promotes branching morphogenesis in mouse salivary glands. In J Oral Biosci on 2024 Mar by Daiki Iwata, Kaori Kometani-Gunjigake,et al..PMID:38246420 , (2024),
PMID: 38246420
et al,Integrating single-cell and spatial analysis reveals MUC1-mediated cellular crosstalk in mucinous colorectal adenocarcinoma , (2024),
PMID:
et al,Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice , (2024),
PMID:

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk
;

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