产品详情
产品名称NR1H4 Polyclonal Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse
免疫原描述Recombinant fusion protein of human NR1H4 (NP_001193908.1).
标记Unconjugated
别名NR1H4; BAR; FXR; HRR-1; HRR1; PFIC5; RIP14; bile acid receptor
数据库入口号Swiss-Prot#:Q96RI1
NCBI Gene ID:9971
Uniprot
Q96RI1
计算分子量59kDa
配方Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using NR1H4 antibody at 1:1000 dilution.
This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.
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et al,Hsa_circ_0001944 Regulates FXR/TLR4 Pathway and Ferroptosis to Alleviate Nickel Oxide Nanoparticles-Induced Collagen Formation in LX-2 Cells
, (2025),
PMID:
40278581
Yes
