产品详情
产品名称SOD1 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total SOD1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human SOD1 (NP_000445.1).
基因/蛋白名称SOD1
标记Unconjugated
别名SOD1;ALS;ALS1;HEL-S-44;IPOA;SOD;hSod1;homodimer
数据库入口号Uniprot:P00441
GeneID:6647
Uniprot
P00441
Gene ID
6647
实际分子量16-18KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using SOD1 antibody.
Immunohistochemistry of paraffin-embedded human liver using SOD1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse kidney using SOD1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat liver using SOD1 Rabbit pAb.
Immunofluorescence analysis of NIH/3T3 cells using SOD1 Rabbit pAb.
Immunofluorescence analysis of U2OS cells using SOD1 Rabbit pAb.
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
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et al,The effect of exposure time and concentration of airborne PM2.5 on lung Injury In mice: A transcriptome analysis. In Redox Biol on 2019 Sep by Wang H, Shen X et al..PMID:31279222
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et al,Alveolar Type II Cell Damage and Nrf2-SOD1 Pathway Downregulation Are Involved in PM2.5-Induced Lung Injury in Rats. In Int J Environ Res Public Health
on 2022 Oct 8 by Rui Niu, Jie Cheng,et al..PMID:36232201
, (2022),
PMID:
36232201
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