产品详情
产品名称SFN Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total SFN protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human 14-3-3 sigma (NP_006133.1).
基因/蛋白名称SFN
标记Unconjugated
别名SFN;YWHAS;stratifin
数据库入口号Uniprot:P31947
GeneID:2810
Uniprot
P31947
Gene ID
2810
实际分子量28KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using 14-3-3 sigma antibody.
Western blot analysis of extracts of various cell lines, using 14-3-3 sigma antibody.
Immunohistochemistry of paraffin-embedded rat skin using 14-3-3 sigma Rabbit pAb.
Immunohistochemistry of paraffin-embedded human skin using 14-3-3 sigma Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse skin using 14-3-3 sigma Rabbit pAb.
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
如果您使用该产品32126发表了文章，请通知我们，让我们可以引用您的文献。
et al,NSUN2-mediated m5C modification of circFAM190B promotes lung cancer progression by inhibiting cellular autophagy.
, (2025),
PMID:
40020806
有货
