产品详情
产品名称NCF2 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous level of total NCF2 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human NOXA2/p67phox (NP_000424.2).
基因/蛋白名称NCF2
标记Unconjugated
别名NCF2;NCF-2;NOXA2;P67-PHOX;P67PHOX
数据库入口号Uniprot:P19878
GeneID:4688
Uniprot
P19878
Gene ID
4688
实际分子量68kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using NOXA2/p67phox antibody.
Immunohistochemistry of paraffin-embedded human esophageal cancer using NOXA2/p67phox Rabbit pAb.
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
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et al,Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.In Parasitol Res on 2015 Feb by Qiang Mao, Zhizhi Xie et al..PMID: 25413629
, (2015),
PMID:
25413629
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