产品详情
产品名称TPM3 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total TPM3 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human TPM3.
基因/蛋白名称TPM3
标记Unconjugated
别名TPM3; FLJ41118; MGC14582; MGC3261; MGC72094
数据库入口号Swiss-Prot:P06753
NCBI Gene ID:7170
Uniprot
P06753
实际分子量33KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Immunofluorescence analysis of HeLa cells using TPM3 antibody. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using TPM3 antibody at 1:1000 dilution.
This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
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et al,Autoantibody against Tumor-Associated Antigens as Diagnostic Biomarkers in Hispanic Patients with Hepatocellular Carcinoma. In Cells on 2022 Oct 14 by Yangcheng Ma, Cuipeng Qiu, et al..PMID:36291095
, (2022),
PMID:
36291095
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