产品详情
产品名称SDC1 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total SDC1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human CD138/Syndecan-1 (NP_002988.3).
基因/蛋白名称SDC1
标记Unconjugated
别名SDC1;CD138;SDC;SYND1;syndecan
数据库入口号Uniprot:P18827
GeneID:6382
Uniprot
P18827
Gene ID
6382
实际分子量85kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of Mouse lung cells, using CD138/Syndecan-1 antibody.
Immunohistochemistry of paraffin-embedded human esophageal cancer using CD138/Syndecan-1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human placenta using CD138/Syndecan-1 Rabbit pAb.
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
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on 2020 Sep by Tomoyoshi Tamura, Motoaki Sano, et al..PMID:32804466
, (2020),
PMID:
32804466
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