产品详情
产品名称CASP7 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total CASP7 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human Caspase-7 (NP_001218.1).
基因/蛋白名称CASP7
标记Unconjugated
别名CASP7;CASP-7;CMH-1;ICE-LAP3;LICE2;MCH3;caspase-7;Casp7
数据库入口号Uniprot:P55210
GeneID:840
Uniprot
P55210
Gene ID
840
实际分子量35KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of Rat liver, using Caspase-7 antibody.
Western blot analysis of extracts of Mouse liver, using Caspase-7 antibody.
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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et al,CD155 Cooperates with PD-1/PD-L1 to Promote Proliferation of Esophageal Squamous Cancer Cells via PI3K/Akt and MAPK Signaling Pathways. In Cancers (Basel) on 2022 Nov 15 by Xiyang Tan, Jie Yang, et al..PMID:36428703
, (2022),
PMID:
36428703
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