产品详情
产品名称G6PD Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total G6PD protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human G6PD (NP_000393.4).
基因/蛋白名称G6PD
标记Unconjugated
别名G6PD;G6PD1
数据库入口号Uniprot:P11413
GeneID:2539
Uniprot
P11413
Gene ID
2539
实际分子量60KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using G6PD antibody.
Immunofluorescence analysis of HeLa cells using G6PD Rabbit pAb.
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
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et al,Activity of glucose-6-phosphate dehydrogenease and its correlation with inflammatory factors in diabetic retinopathy. In PLoS One
on 2024 Dec 2 by Dan Liu, Chuchu Cheng,et al..PMID:39621725
, (2024),
PMID:
39621725
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