产品详情
产品名称BTK Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total BTK protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human BTK (NP_000052.1).
基因/蛋白名称BTK
标记Unconjugated
别名AGMX1;AT;ATK;BPK;IMD1;PSCTK1;XLA;BTK
数据库入口号Uniprot:Q06187
GeneID:695
Uniprot
Q06187
Gene ID
695
实际分子量Refer to Figures
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Immunohistochemistry of paraffin-embedded mouse spleen using BTK antibody.
Immunohistochemistry of paraffin-embedded rat spleen using BTK antibody.
Immunohistochemistry of paraffin-embedded mouse brain using BTK antibody.
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
如果您使用该产品32321发表了文章，请通知我们，让我们可以引用您的文献。
et al,BAP31 Plays an Essential Role in Mouse B Cell Development via Regulation of BCR Signaling. In Int J Mol Sci on 2024 May 2
by Bo Zhao, Fei An,et al..PMID:38732181
, (2024),
PMID:
38732181
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