产品详情
产品名称NPPA Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total NPPA protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human NPPA.
基因/蛋白名称NPPA
标记Unconjugated
别名ANF; ANP; PND; ATFB6; CDD-ANF
数据库入口号Swiss-Prot:P01160
NCBI Gene ID:4878
Uniprot
P01160
实际分子量17KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using NPPA antibody at 1:1000 dilution.
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.
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et al,Design, Synthesis, and Evaluation of the Selective and Orally Active LSD1 Inhibitor with the Potential of Treating Heart Failure
, (2024),
PMID:
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