产品详情
产品名称IFNAR1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total IFNAR1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human IFNAR1.
基因/蛋白名称IFNAR1
标记Unconjugated
别名AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC
数据库入口号Swiss-Prot:P17181
NCBI Gene ID:3454
Uniprot
P17181
实际分子量63KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using IFNAR1 antibody at 1:1000 dilution.
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
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et al,Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D.In J Exp Clin Cancer Res. On 2018 Nov 27 by Qiang Z, Zhou ZY et al..PMID: 30482227
, (2018),
PMID:
30482227
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