产品详情
产品名称GRIA1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB IHC IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total GRIA1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human GRIA1.
基因/蛋白名称GRIA1
标记Unconjugated
别名GLUH1; GLUR1; GLURA; GluA1; HBGR1
数据库入口号Swiss-Prot:P42261
NCBI Gene ID:2890
Uniprot
P42261
实际分子量105KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100
Immunofluorescence: 1:50 - 1:200
Western blot analysis of extracts of Rat brain cell line, using GRIA1 antibody.
Immunohistochemistry of paraffin-embedded human stomach cancer using GRIA1 antibody at dilution of 1:200 (x400 lens)
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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et al,The extracellular fragment of GPNMB (Glycoprotein nonmelanosoma protein B, osteoactivin) improves memory and increases hippocampal GluA1 levels in mice.In J Neurochem on 2015 Mar by Kenta Murata, Yuta Yoshino et al..PMID: 25545823
, (2015),
PMID:
25545823
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