产品详情
产品名称ARG1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total ARG1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human ARG1.
基因/蛋白名称ARG1
标记Unconjugated
别名ARG1; Arginase-1; Liver-typearginase; TypeIarginase;
数据库入口号Swiss-Prot:P05089
NCBI Gene ID:383
Uniprot
P05089
实际分子量35KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunofluorescence analysis of Rat liver using ARG1 / Arginase 1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Human liver using ARG1 / Arginase 1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of Mouse liver using ARG1 / Arginase 1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using ARG1 / Arginase 1 antibody at 1:2000 dilution.
Immunohistochemistry of paraffin-embedded mouse liver using ARG1 / Arginase 1 antibody at dilution of 1:100 (40x lens).
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
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