产品详情
产品名称SLC25A4 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB;IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total SLC25A4 protein.
免疫原类型Recombinant Protein
免疫原描述Synthetic peptide of human SLC25A4
基因/蛋白名称SLC25A4
标记Unconjugated
别名SLC25A4;AAC1;ANT;ANT 1;ANT1;MTDPS12;MTDPS12A;PEO2;PEO3;PEOA2;T1
数据库入口号Uniprot:P12235
GeneID:291
Uniprot
P12235
Gene ID
291
实际分子量33KDa
浓度1.0mg/ml
配方pH7.4 PBS, 0.05% NaN3, 40% Glycerol
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:1000-1:5000;
IHC 1:50-1:200;
Gel: 12%SDS-PAGE
Lysate: 40 ug
Lane: Mouse heart tissue lysate
Primary antibody: (SLC25A4 Antibody) at dilution 1/800
Secondary antibody: (HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution
Exposure time: 10 seconds
The image on the left is immunohistochemistry of paraffinembedded Human liver cancer tissue using (SLC25A4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: 200)
The image on the left is immunohistochemistry of paraffinembedded Human breast cancer tissue using (SLC25A4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: 200)
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy.
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et al,Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. In Sci Adv on 2019 Aug 28 by Karch J, Bround MJ, et al..PMID:31489369
, (2019),
PMID:
31489369
et al,ATP synthase C-subunit-deficient mitochondria have a small cyclosporine A-sensitive channel, but lack the permeability transition pore. In Cell Rep on 2019 Jan 2 by Maria A Neginskaya, Maria E Solesio, et al..PMID: 30605668
, (2019),
PMID:
30605668
et al,A mitochondrial megachannel resides in monomeric F 1 FO ATP synthase. In Nat Commun on 2019 Dec 20 by Nelli Mnatsakanyan, Marc C Llaguno,et al..PMID: 31862883
, (2019),
PMID:
31862883
et al,ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophyInSci AdvOn2023 Aug 25byMichael J Bround?1,?Julian R Havens et al..PMID: 37624892
, (2023),
PMID:
37624892
et al,The adenine nucleotide translocase family underlies cardiac ischemia-reperfusion injury through the mitochondrial permeability pore independently of cyclophilin D
, (2024),
PMID:
et al,DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice
, (2024),
PMID:
有货
