产品详情
产品名称PCK1 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total PCK1 protein.
免疫原类型Peptide
免疫原描述A synthetic peptide of human PCK1 (NP_002582.3).
基因/蛋白名称PCK1
标记Unconjugated
别名PCK1;PEPCK-C;PEPCK1;PEPCKC
数据库入口号Uniprot:P35558
GeneID:5105
Uniprot
P35558
Gene ID
5105
实际分子量69KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:1000 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using PCK1 antibody.
Western blot analysis of extracts of HepG2 cells, using PCK1 antibody.
Immunofluorescence analysis of rat kidney using PCK1 Rabbit pAb.
Immunofluorescence analysis of human kidney cancer using PCK1 Rabbit pAb.
Immunofluorescence analysis of mouse kidney using PCK1 Rabbit pAb.
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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et al,Important role of 5鈥恏ydroxytryptamine in glucocorticoid鈥恑nduced insulin resistance in liver and intra鈥恆bdominal adipose tissue of rats.In J Diabetes Investig on 2016 Jan by Tao Li , Keke Guo et al..PMID:26816599
, (2016),
PMID:
26816599
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