产品详情
产品名称HDAC2 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total HDAC2 protein.
免疫原类型Peptide
免疫原描述A synthetic peptide of human HDAC2 (NP_001518.3).
基因/蛋白名称HDAC2
标记Unconjugated
别名HD2;RPD3;YAF1;HDAC2
数据库入口号Uniprot:Q92769
GeneID:3066
Uniprot
Q92769
Gene ID
3066
实际分子量60kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using HDAC2 antibody.
Immunohistochemistry of paraffin-embedded rat kidney using HDAC2 antibody.
Immunohistochemistry of paraffin-embedded human esophageal cancer using HDAC2 antibody.
Immunohistochemistry of paraffin-embedded mouse heart using HDAC2 antibody.
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
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et al,A comprehensive analysis of oxidative stress in the ozone-induced lung inflammation mouse model. In Clin Sci (Lond) on 2014 Mar
by Coen H Wiegman, Feng Li, et al..PMID: 24040961
, (2014),
PMID:
24040961
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