产品详情
产品名称IGF2 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total IGF2 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human IGF2 (NP_000603.1).
基因/蛋白名称IGF2
标记Unconjugated
别名IGF2;C11orf43;GRDF;IGF-II;PP9974
数据库入口号Uniprot:P01344
GeneID:3481
Uniprot
P01344
Gene ID
3481
实际分子量20KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100
Western blot analysis of extracts of HepG2 cells, using IGF2 antibody.
Immunohistochemistry of paraffin-embedded human placenta using IGF2 Rabbit pAb.
Immunofluorescence analysis of HepG2 cells using IGF2 Rabbit pAb.
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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et al,HMGA1P7-pseudogene regulates H19 and Igf2 expression by a competitive endogenous RNA mechanism. In Sci Rep on 2016 Nov 22 by Marco De Martino, Floriana Forzati, et al..PMID: 27874091
, (2016),
PMID:
27874091
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