产品详情
产品名称IL1RN Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total IL1RN protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human IL1RA (NP_000568.1).
基因/蛋白名称IL1RN
标记Unconjugated
别名IL1RN;DIRA;ICIL-1RA;IL-1RN;IL-1ra;IL-1ra3;IL1F3;IL1RA;IRAP;MVCD4
数据库入口号Uniprot:P18510
GeneID:3557
Uniprot
P18510
Gene ID
3557
实际分子量18KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of A-431 cells, using IL1RA antibody.
Immunofluorescence analysis of human skin cancer using IL1RA Rabbit pAb.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
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et al,Expression and function of interleukin锟?尾 is required for hamster blastocyst hatching: Involvement of hatching鈥恆ssociated cathepsin proteases In Mol Reprod Dev on 2021 Apr
by Madhulika Pathak, Venkatappa Vani,et al..PMID:33719101
, (2021),
PMID:
33719101
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