产品详情
产品名称FOXM1 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total FOXM1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human FOXM1 (NP_973732.1).
基因/蛋白名称FOXM1
标记Unconjugated
别名FKHL16;FOXM1B;HFH-11;HFH11;HNF-3;INS-1;MPHOSPH2;MPP-2;MPP2;PIG29;TRIDENT;FOXM1
数据库入口号Uniprot:Q08050
GeneID:2305
Uniprot
Q08050
Gene ID
2305
实际分子量110KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using FOXM1 antibody.
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.
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et al,Sphingosine-1-phosphate induces airway smooth muscle cell proliferation, migration, and contraction by modulating Hippo signaling effector YAP.In Am J Physiol Lung Cell Mol Physiol. On 2018 Oct 1 by Liu L, Zhai C et al..PMID: 29999407
, (2018),
PMID:
29999407
et al,Activation of autophagy induces monocrotalineinduced pulmonary arterial hypertension by FOXM1-mediated FAK phosphorylation . In Lung on 2022 Oct by Cui Zhai, Nana Zhang, et al..PMID:36107242
, (2022),
PMID:
36107242