产品详情
产品名称ECE1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total ECE1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human ECE1.
基因/蛋白名称ECE1
标记Unconjugated
别名ECE;
数据库入口号Swiss-Prot:P42892
NCBI Gene ID:1889
Uniprot
P42892
实际分子量87KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Western blot analysis of extracts of mouse liver, using ECE1 antibody at 1:1000 dilution.
Immunofluorescence analysis of L929 cells using ECE1 Polyclonal antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded rat spleen using ECE1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human mammary cancer using ECE1 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using ECE1 antibody at dilution of 1:100 (40x lens).
The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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et al,Phenylethanol Glycosides Protect Myocardial Hypertrophy Induced by Abdominal Aortic Constriction via ECE-1 Demethylation Inhibition and PI3K/PKB/eNOS Pathway Enhancement. In Evid Based Complement Alternat Med on 2020 Jun 9 by Qiong-Ling Fan, Jia-Wei Wang, et al..PMID:32595726
, (2020),
PMID:
32595726
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