产品详情
产品名称TRPV4 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB
种属反应性Human;Mouse
特异性The antibody detects endogenous level of total TRPV4 protein.
免疫原类型Recombinant Protein
免疫原描述A synthetic peptide of human TRPV4 (NP_067638.3).
基因/蛋白名称TRPV4
标记Unconjugated
别名TRPV4;BCYM3;CMT2C;HMSN2C;OTRPC4;SMAL;SPSMA;SSQTL1;TRP12;VRL2;VROAC
数据库入口号Uniprot:Q9HBA0
GeneID:59341
Uniprot
Q9HBA0
Gene ID
59341
实际分子量95KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
Western blot analysis of extracts of Mouse heart, using TRPV4 antibody.
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.
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et al,Aortic smooth muscle TRPV4 channels regulate vasoconstriction in high salt-induced hypertensionInHypertens ResOn2023 OctbyXin Wen?#?1,?Yidi Peng et al..PMID:?37532951
, (2023),
PMID:
37532951
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