产品详情
产品名称GRB7 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total GRB7 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human GRB7.
基因/蛋白名称GRB7
标记Unconjugated
数据库入口号Swiss-Prot:Q14451
NCBI Gene ID:2886
Uniprot
Q14451
实际分子量59KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using GRB7 antibody.
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.
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et al,Chromosome instability region analysis and identification of the driver genes of the epithelial ovarian cancer cell lines A2780 and SKOV3InJ Cell Mol MedOn2023 NovbyJianxiong Li?1,?Zexin Chen et al..PMID: 37525498
, (2023),
PMID:
37525498
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