产品详情
产品名称MAVS Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total MAVS protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human MAVS (NP_065797.2).
基因/蛋白名称MAVS
标记Unconjugated
别名CARDIF;IPS-1;IPS1;VISA;MAVS
数据库入口号Uniprot:Q7Z434
GeneID:57506
Uniprot
Q7Z434
Gene ID
57506
实际分子量70kDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MAVS antibody.
Immunohistochemistry of paraffin-embedded Rat ovary using MAVS antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using MAVS antibody.
Immunohistochemistry of paraffin-embedded human stomach using MAVS antibody.
Immunohistochemistry of paraffin-embedded Mouse heart using MAVS antibody.
Immunofluorescence analysis of NIH-3T3 cells using MAVS Rabbit pAb.
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene.
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et al,Enterovirus 71 protease 2Apro targets MAVS to inhibit anti-viral type I interferon responses. In PLoS Pathog on 2013 Mar by Bei Wang, Xueyan Xi, et al..PMID: 23555247
, (2013),
PMID:
23555247
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