产品详情
产品名称JMJD6 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by affinity purification using immunogen.
应用WB,IHC,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total JMJD6 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant protein of human JMJD6.
基因/蛋白名称JMJD6
标记Unconjugated
别名PSR; PTDSR; PTDSR1;
数据库入口号Swiss-Prot:Q6NYC1
NCBI Gene ID:23210
Uniprot
Q6NYC1
实际分子量46KD
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Immunohistochemistry of paraffin-embedded rat pancreas using JMJD6 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using JMJD6 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse testis using JMJD6 antibody at dilution of 1:100 (40x lens).
Western blot analysis of extracts of mouse liver, using JMJD6 antibody at 1:1000 dilution.
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
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et al,KRas-ERK signallIng promotes the onset and maIntenance of uveal melanoma through regulatIng JMJD6-mediated H2A.X phosphorylation at tyrosIne 39.In Artif Cells Nanomed Biotechnol on 2019 Dec by Li Y, Yu P, et al..PMID:31736361
, (2019),
PMID:
31736361
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