产品详情
产品名称SETDB1 Antibody
来源种属Rabbit
克隆性Polyclonal
亚型IgG
纯化Affinity purification
应用WB,IF
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous level of total SETDB1 protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fusion protein of human SETDB1 (NP_001230420.1).
基因/蛋白名称SETDB1
标记Unconjugated
别名SETDB1;ESET;H3-K9-HMTase4;KG1T;KMT1E;TDRD21
数据库入口号Uniprot:Q15047
GeneID:9869
Uniprot
Q15047
Gene ID
9869
实际分子量180KDa
浓度1.0mg/ml
配方PBS with 0.02% sodium azide,50% glycerol,pH7.3.
保存Store at -20˚C. Avoid freeze / thaw cycles.
应用详情
WB 1:500 - 1:2000
IF 1:50 - 1:100
Western blot analysis of extracts of various cell lines, using SETDB1 antibody.
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
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et al,Autoantibody against Tumor-Associated Antigens as Diagnostic Biomarkers in Hispanic Patients with Hepatocellular Carcinoma. In Cells on 2022 Oct 14 by Yangcheng Ma, Cuipeng Qiu, et al..PMID:36291095
, (2022),
PMID:
36291095
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