产品详情
产品名称ARG1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total ARG1 protein.
免疫原类型Peptide
免疫原描述Synthesized peptide derived from internal of human ARG1.
基因/蛋白名称ARG1
标记Unconjugated
别名AI; AI256583; Arg-1; ARGI1; arginase 1
数据库入口号Swiss-Prot: P05089
NCBI Gene ID: 383
Uniprot
P05089
实际分子量35kd
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from 293 cells and A549 cells, using ARG1antibody #34437.
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
Haraguchi Y., Proc. Natl. Acad. Sci. U.S.A. 84:412-415(1987).
Takiguchi M., Nucleic Acids Res. 16:8789-8802(1988).
Mungall A.J., Nature 425:805-811(2003).
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