产品详情
产品名称IL4 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total IL4 protein.
免疫原类型Peptide
免疫原描述Synthesized peptide derived from C-terminal of human IL4.
基因/蛋白名称IL4
标记Unconjugated
别名 B cell growth factor 1; B cell stimulatory factor 1; B-cell stimulatory factor 1; BCGF-1; BCGF1
数据库入口号Swiss-Prot: P05112
NCBI Gene ID: 3565
Uniprot
P05112
实际分子量18kd
浓度1.0mg/ml
配方Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500~1:3000
Western blot analysis of extracts from HeLa cells, using IL4 antibody #35227.
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
Yokota T., Proc. Natl. Acad. Sci. U.S.A. 83:5894-5898(1986).
Arai N., J. Immunol. 142:274-282(1989).
Klein S.C., Immunogenetics 41:57-57(1995).
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PMID:
35944117
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