产品详情
产品名称mTOR Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were purified by antigen-affinity chromatography.
应用WB
种属反应性Human
特异性The antibody detects endogenous levels of total mTOR protein.
免疫原类型Recombinant Protein
免疫原描述Recombinant fragment corresponding to a region within amino acids 1287 and 1569 of mTOR.
基因/蛋白名称mTOR
标记Unconjugated
别名FLJ44809 antibody; FRAP antibody; FRAP1 antibody; FRAP2 antibody; RAFT1 antibody; RAPT1 antibody; MTOR antibody; FK506 binding protein 12-rapamycin associated protein 2 antibody; FK506-binding protein 12-rapamycin complex-associated protein 1 antibody; FK
数据库入口号Swiss-Prot#:P42345;
NCBI Gene#:2475
Uniprot
P42345
实际分子量289kd
浓度1mg/ml
配方Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:3000
Sample (30 ug of whole cell lysate)
A: Raji
5% SDS PAGE
#35373 diluted at 1:1000
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq]
如果您使用该产品35373发表了文章，请通知我们，让我们可以引用您的文献。
et al,Amlexanox Enhances Temozolomide-Induced Antitumor Effects in Human Glioblastoma Cells by Inhibiting IKBKE and the Akt-mTOR Signaling Pathway. In ACS Omega on 2021 Feb 5 by Jinbiao Xiong, Gaochao Guo, et al..PMID:33644550
, (2020),
PMID:
33644550
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