产品详情
产品名称TRIM29 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total TRIM29 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to residues near the N terminal of human tripartite motif containing 29
基因/蛋白名称TRIM29
标记Unconjugated
别名ATDC
数据库入口号Swiss-Prot#: Q14134
NCBI Gene ID: 23650
Gene Accssion: BC017352
Uniprot
Q14134
实际分子量66kd
浓度2.2mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 8%SDS-PAGE
Lysate: 40ug HT-29 cell
Primary antibody: 1/400 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 seconds
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #35641 at dilution 1/50.
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
如果您使用该产品35641发表了文章，请通知我们，让我们可以引用您的文献。
et al,Upregulated expression of ACTL8 contributes to Invasion and metastasis and indicates poor prognosis In colorectal cancer. In Onco Targets Ther on 2019 Mar 1 by Han Q, Sun ML, et al.. PMID: 30881029
, (2019),
PMID:
30881029
et al,Transcriptional dysregulation of TRIM29 promotes colorectal cancer carcinogenesis via pyruvate kinase-mediated glucose metabolism. In Aging (Albany NY) on 2021 Jan 20 by Jing Han, Zitong Zhao, et al..PMID:33495406
, (2021),
PMID:
33495406
et al,TRIM29 is differentially expressed in colorectal cancers of different primary locations and affects survival by regulating tumor immunity
based on retrospective study and bioinformatics analysis. In J Gastrointest Oncol on 2022 Jun by Jing Han, Jing Zuo,et al..PMID:35837175
, (2022),
PMID:
35837175
有货
