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ERBB4 Antibody#35681

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产品详情

产品名称ERBB4 Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antigen affinity purification.

应用WB IHC

种属反应性Human;Mouse;Rat

特异性The antibody detects endogenous levels of total ERBB4 protein.

免疫原类型Recombinant Protein

免疫原描述Fusion protein corresponding to a region derived from internal residues of human v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

基因/蛋白名称ERBB4

标记Unconjugated

别名HER4; ALS19; p180erbB4

数据库入口号Swiss-Prot#: Q15303
NCBI Gene ID: 2066
Gene Accssion: BC112199/Q15303

Uniprot Q15303

实际分子量147kd

浓度1.7mg/ml

配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

保存Store at -20˚C

应用详情

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Gel: 6%SDS-PAGE
Lysate: 40ug Hela cell
Primary antibody: 1/200 dilution
Secondary antibody dilution: 1/8000
Exposure time: 5 seconds
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #35681 at dilution 1/40.

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation.?

如果您使用该产品35681发表了文章，请通知我们，让我们可以引用您的文献。

et al,MicroRNA锟?46b, a sensitive indicator of mesenchymal stem cell repair of acute renal injury.In Stem Cells Transl Med on 2016 Oct by Yuan Zhu, Jing Yu et al..PMID:27400799 , (2016),
PMID: 27400799
et al,MicroRNA-146b, a sensitive indicator of mesenchymal stem cell repair of acute renal injury. In Stem Cells Transl Med on 2016 Oct by Yuan Zhu, Jing Yu, et al..PMID: 27400799 , (2016),
PMID: 27400799
et al,The Notch1/Hes1 pathway regulates Neuregulin 1/ErbB4 and participates in microglial activation in rats with VPA-induced autism. In Prog Neuropsychopharmacol Biol Psychiatry on 2024 Apr 20 by Yanan Deng, Liping Ma, et al..PMID:38242426 , (2024),
PMID: 38242426

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注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu人
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk猴
  • Rb兔
  • B牛
  • D狗
  • P猪
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk鸡
;

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