产品详情
产品名称ITGB1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total ITGB1 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to a region derived from internal residues of human integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
基因/蛋白名称ITGB1
标记Unconjugated
别名CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA
数据库入口号Swiss-Prot#: P05556
NCBI Gene ID: 3688
Gene Accssion: BC020057
Uniprot
P05556
实际分子量88kd
浓度2.4mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 6%SDS-PAGE
Lysates (from left to right): A172 cell and human leiomyosarcoma tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/600 dilution
Secondary antibody dilution: 1/8000
Exposure time: 40 seconds
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using #35784 at dilution 1/60.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
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et al,Effects of the integrin inhibitors BTT3033 and BOP, and the integrin-linked kinase inhibitor Cpd22 on human prostate smooth muscle contraction
, (2021),
PMID:
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