产品详情
产品名称RGS2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB;IHC
种属反应性Human;Mouse;Rat
特异性The antibody detects endogenous levels of total RGS2 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to a region derived from internal residues of human Egulator of G-protein signaling 2, 24kDa
基因/蛋白名称RGS2
标记Unconjugated
别名G0S8
数据库入口号Swiss-Prot#: P41220
NCBI Gene ID: 5997
Gene Accssion: BC007049
Uniprot
P41220
实际分子量24kd
浓度1.4mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 12%SDS-PAGE
Lysates (from left to right): Human fetal lung tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/800 dilution
Secondary antibody dilution: 1/8000
Exposure time: 40 seconds
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #35906 at dilution 1/20.
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
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et al,Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer
, (2024),
PMID: