产品详情
产品名称TPH1 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用IHC
种属反应性Human
特异性The antibody detects endogenous levels of total TPH1 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to residues near the C terminal of human tryptophan hydroxylase 1
基因/蛋白名称TPH1
标记Unconjugated
别名TPRH; TRPH
数据库入口号Swiss-Prot#: P17752
NCBI Gene ID: 7166
Gene Accssion: BC106739
Uniprot
P17752
浓度0.7mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Immunohistochemistry: 1:15-1:50
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #35965 at dilution 1/20.
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using #35965 at dilution 1/20.
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
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et al,The activation of 5-hydroxytryptamine degradation system in proximal renal tubular epithelial cells induced by renal ischemia-reperfusion injury
, (2021),
PMID:
et al,Nephrotoxicity induced by cisplatin is primarily due to the activation of the 5-hydroxytryptamine degradation system in proximal renal tubules
, (2021),
PMID:
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