产品详情
产品名称SUFU Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human
特异性The antibody detects endogenous levels of total SUFU protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to residues near the C terminal of human Suppressor of fused homolog (Drosophila)
基因/蛋白名称SUFU
标记Unconjugated
别名SUFUH; SUFUXL; PRO1280
数据库入口号Swiss-Prot#: Q9UMX1
NCBI Gene ID: 51684
Gene Accssion: BC013291
Uniprot
Q9UMX1
实际分子量54kd
浓度0.5mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
Gel: 10%SDS-PAGE
Lysate: 50ug Jurkat cell
Primary antibody: 1/100 dilution
Secondary antibody dilution: 1/8000
Exposure time: 10 seconds
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #35993 at dilution 1/10.
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
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et al,Suppressor of Fused (Sufu) Mediates the Effect of Parathyroid Hormone-Like Hormone (Pthlh) on Chondrocyte Differentiation in the Growth Plate.In J Biol Chem on 2012 Oct 19 by Xiaoyun Zhang, Steven Cheng, et al..PMID:22930757
, (2012),
PMID:
22930757
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