产品详情
产品名称AK2 Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antigen affinity purification.
应用WB IHC
种属反应性Human;Mouse
特异性The antibody detects endogenous levels of total AK2 protein.
免疫原类型Recombinant Protein
免疫原描述Fusion protein corresponding to residues near the N terminal of human adenylate kinase 2
基因/蛋白名称AK2
标记Unconjugated
别名ADK2; AK 2
数据库入口号Swiss-Prot#: P54819
NCBI Gene ID: 204
Gene Accssion: BC009405
Uniprot
P54819
实际分子量26kd
浓度1.6mg/ml
配方Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
保存Store at -20˚C
应用详情
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Gel: 10%SDS-PAGE
Lysates (from left to right): Human placenta tissue and A549 cell, mouse brain tissue and hepG2 cell, Raji cell and human fetal liver tissue, hela cell
Amount of lysate: 40ug per lane
Primary antibody: 1/300 dilution
Secondary antibody dilution: 1/8000
Exposure time: 20 seconds
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using #36210 at dilution 1/40.
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
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et al,Effects of the Nonsteroidal Anti-inflammatory Drug Celecoxib on Mitochondrial Function.In Biol Pharm Bull. On 2018 by Tatematsu Y, Fujita H et al..PMID:29491208
, (2018),
PMID:
29491208
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